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The 1944 Illinois Fighting Illini football team was an American football team that represented the University of Illinois during the 1944 college football season. In their seventh season under head coach Ray Eliot, the Illini compiled a 4–3–1 record and finished in second place in the Big Ten Conference. The team played its home games at Memorial Stadium in Champaign, Illinois.

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Illinois Fighting Illini
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Expression of high levels of prokaryotic-type porphyrogenic enzymes in E. coli provides a useful system to study the biosynthetic formation of an iron-containing intermediate, and the ensuing covalent attachment of heme. We are developing this system to examine the positioning of the iron-bound intermediates, iron-free steps and the mechanism of covalent attachment of heme. Here, we show that porphobilinogen (PBG) can serve as a heme precursor in E. coli. Labeling studies were performed with meso-(14)C-PBG. This was shown by selective extraction of (14)C labeled PBG and an increase in the (14)C level of heme. Iron-free steps were accomplished by treating cells with nitrilotriacetic acid (NTA), which disrupts iron coordination on proteins. Labeling studies using NTA indicated the presence of an unidentified PBG derivative. N-terminal sequencing of the protein confirmed the identity of this derivative as aminovaleric PBG. Incubation of protein extracts with iron protoporphyrin IX resulted in covalent attachment of a heme molecule. The heme could be readily distinguished from free heme and protein. Porphobilinogen synthase produced heme from PBG, demonstrating that the synthase catalyzes heme attachment to the precursor in E. coli. This provides the first direct evidence that covalent attachment of heme to a heme intermediate is a general step in heme biosynthesis.Q:

Is there a word for people who hate computers?

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Does that mean people who are afraid of computers? Or can’t use them? Or need someone else to do everything for them? Or like controlling them and anything they do on a computer?
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You could also be called a Luddite.